Biostatistical Analyses

Laajala TD, Jumppanen M, Huhtaniemi R, Fey V, Kaur A, Knuuttila M, Aho E, Oksala R, Westermarck J, Mäkelä S, Poutanen M, Aittokallio T. Optimized design and analysis of preclinical intervention studies in vivo. Scientific Reports 2016, 6; 30723. doi:10.1038/srep30723

Vehmas AP, Adam M, Laajala TD, Kastenmüller G, Prehn C, Rozman J, Ohlsson C, Fuchs H, Hrabe de Angelis M, Gailus-Durner V, Elo LL, Aittokallio T, Adamski J, Corthals G, Poutanen M, Strauss L. Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse. J Proteomics 133:66-75, 2016
http://www.ncbi.nlm.nih.gov/pubmed/26691839

Cardiovascular Analyses

Rinne P, Ahola-Olli A, Nuutinen S, Koskinen E, Eerola K, Juonala M, Kähönen M, Lehtimäki T, Raitakari OT, Savontaus E. Deficiency in Melanocortin 1 Receptor Signaling Predisposes to Vascular Endothelial Dysfunction and Increased Arterial Stiffness in Mice and Humans. Arterioscler Thromb Vasc Biol 2015 Apr 30. pii: ATVBAHA.114.305064
http://www.ncbi.nlm.nih.gov/pubmed/25931512

Intestinal diseases

Lähdeniemi IAK, Misiorek JO, Antila CJM, Landor SK, Stenvall CA, Fortelius LE, Bergström LK, Sahlgren C, Toivola DM. Keratins regulate colonic epithelial cell differentiation through the Notch1 signalling pathway. Cell Death Differ. 2017 Jun;24(6):984-996.
https://www.ncbi.nlm.nih.gov/pubmed/28475172

Nutrition and Metabolism Analyses

Ali I, Hurmerinta T, Nurmi T, Berglund M, Rüegg J, Poutanen M, Halldin K, Mäkelä S, Damdimopoulou P. From pure compounds to complex exposure: Effects of dietary cadmium and lignans on estrogen, epidermal growth factor receptor, and mitogen activated protein kinase signaling in vivo. Toxicol Lett.  Jun 24;253:27-35, 2016
http://www.ncbi.nlm.nih.gov/pubmed/27108949

PET Imaging

Laurila PP, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, Kaiharju E, Coomans CP, Van Den Berg SA, Autio A, Sarin AP, Kettunen J, Tikkanen E, Manninen T, Metso J, Silvennoinen R, Merikanto K, Ruuth M, Perttilä J, Mäkelä A, Isomi A, Tuomainen AM, Tikka A, Ramadan UA, Seppälä I, Lehtimäki T, Eriksson J, Havulinna A, Jula A, Karhunen PJ, Salomaa V, Perola M, Ehnholm C, Lee-Rueckert M, Van Eck M, Roivainen A, Taskinen MR, Peltonen L, Mervaala E, Jalanko A, Hohtola E, Olkkonen VM, Ripatti S, Kovanen PT, Rensen PC, Suomalainen A, Jauhiainen M. USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.  Sci Transl Med. 2016 Jan 27;8(323):323ra13. doi: 10.1126/scitranslmed.aad0015.
https://www.ncbi.nlm.nih.gov/pubmed/26819196

Reproductive Analyses

Vehmas AP, Adam M, Laajala TD, Kastenmüller G, Prehn C, Rozman J, Ohlsson C, Fuchs H, Hrabě de Angelis M, Gailus-Durner V, Elo LL, Aittokallio T, Adamski J, Corthals G, Poutanen M, Strauss L. Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse. J Proteomics. 133:66-75, 2016
http://www.ncbi.nlm.nih.gov/pubmed/26691839

Björkgren I, Alvarez L, Blank N, Balbach M, Turunen H, Laajala TD, Toivanen J, Krutskikh A, Wahlberg N, Huhtaniemi I, Poutanen M, Wachten D, Sipilä P. Targeted inactivation of the mouse beta-defensin41 alters sperm flagellar beat pattern and zona pellucida binding. Mol Cell Endocrinol 427:143-54, 2016
http://www.ncbi.nlm.nih.gov/pubmed/26987518