The authors (Aittokallio, Scherer, Poutanen, Freedman) within the article (http://stm.sciencemag.org/content/9/389/eaal4101.short ) emphasize the importance of applying better baseline stratification factors during the preclinical studies to improve the fitness and quality of the models and their translatability to clinical trials. Tools for improving the analyses have also been recently developed by TCDM (https://biomedportal.utu.fi/utu-apps/Rvivo/ ), and scientists are encouraged to apply these tools to further improve the quality of their studies.
At TCDM we are continuously searching solutions for the problems faced by endometriosis patients, physicians and researchers. We are searching for new treatment strategies, aims to improve diagnostics and developing new preclinical models for the disease, e.g. by using patient derived cell lines. Active research over 10 years have resulted in more than 10 scientific publications.
11th Disease Modeling symposium, Cancer and Metabolism, was organized December 13 -14, 2016. The symposium focused on specific aspects of studying cancer and metabolism.
The Director of the TCDM, Matti Poutanen, and the Coordinator/PI of Intestinal Diseases Unit, Diana Toivola, renewed their Endocrinological Research Grants from Novo Nordisk Foundation. Congratulations!
FLIR T620 Infrared Camera has been purchased by the Institute of Biomedicine, the University of Turku. The camera is suitable for thermal imaging of experimental animals, and allows measuring eg. brown adipose tissue temperature in awake, freely moving animals. The camera and imaging service is available in Nutrition and Metabolism Unit.
CASA – computer assisted sperm analyzer, CEROS II from Hamilton Thorne has been purchased by the Institute of Biomedicine at the University of Turku. Detailed sperm analysis include: sperm counts and concentrations, motility, velocity and kinematic measures. Analyses are now available in Reproductive Biology Unit.
TCDM has generated the first knock-out mouse models using CRISPR-Cas9 technology. Service is now available for generation of genetically modified mouse models. See more from our web pages.
The Institute of Biomedicine at the University of Turku has purchased a Faxitron MultiRad 350 irradiator, for biological material. The instrument is a fully-shielded, self-contained X-ray irradiator which is a safer alternative to radioisotope irradiators. The device is the first of its kind in Nordic countries, and it will be used for irradiating various biological materials such as cells and small experimental animals.
The Director of the TCDM, Matti Poutanen, and the Coordinator/PI of Intestinal Diseases Unit, Diana Toivola, were granted by Novo Nordisk Foundation from Endocrinological Research Grants. Congratulations!