Rinne P, Ahola-Olli A, Nuutinen S, Koskinen E, Eerola K, Juonala M, Kähönen M, Lehtimäki T, Raitakari OT, Savontaus E. Deficiency in Melanocortin 1 Receptor Signaling Predisposes to Vascular Endothelial Dysfunction and Increased Arterial Stiffness in Mice and Humans. Arterioscler Thromb Vasc Biol 2015 Apr 30. pii: ATVBAHA.114.305064
http://www.ncbi.nlm.nih.gov/pubmed/25931512

Rinne PP,  Ståhle M, Hellberg S, Silvola J, Salomäki H, Koskinen E, Nuutinen S, Saraste A, Roivainen A, Savontaus E. Pharmacological Activation of the Melanocortin System Limits Plaque Inflammation and Ameliorates Vascular Dysfunction in Atherosclerotic Mice. Arterioscler Thromb Vasc Biol. Jul;34(7):1346-54, 2014
http://www.ncbi.nlm.nih.gov/pubmed/24790139

Rinne P, Nordlund W, Heinonen I, Penttinen AM, Saraste A, Ruohonen ST, Mäkelä S, Vähätalo L, Kaipio K, Cai M, Hruby VJ, Ruohonen S, Savontaus E. α-Melanocyte-stimulating hormone regulates vascular NO availability and protects against endothelial dysfunction. Cardiovasc Res. 97:360-368, 2013
http://www.ncbi.nlm.nih.gov/pubmed/23131503

Rinne P, Harju J, Mäkelä S, Savontaus E. Genetic and pharmacologic mouse models of chronic melanocortin activation show enhanced baroreflex control of heart rate, Regul Pept. 182:19-27, 2013
http://www.ncbi.nlm.nih.gov/pubmed/23327996

Rinne P, Penttinen AM, Nordlund W, Ahotupa M, Savontaus E. α-MSH Analogue Attenuates Blood Pressure Elevation in DOCA-Salt Hypertensive Mice. PLoS One 8(8):e72857, 2013
http://www.ncbi.nlm.nih.gov/pubmed/23977363

Rinne P, Tikka S, Mäkelä S, Streng T, Savontaus E. Hemodynamic actions and mechanisms of systemically administered α-MSH analogs in mice. Peptides. 38: 150-158, 2012
http://www.ncbi.nlm.nih.gov/pubmed/22982611