UTU

Lähdeniemi IAK, Misiorek JO, Antila CJM, Landor SK, Stenvall CA, Fortelius LE, Bergström LK, Sahlgren C, Toivola DM. Keratins regulate colonic epithelial cell differentiation through the Notch1 signalling pathway. Cell Death Differ. 2017 Jun;24(6):984-996.
https://www.ncbi.nlm.nih.gov/pubmed/28475172

Helenius TO, Antman CA, Asghar MN, Nyström JH, Toivola DM. Keratins Are Altered in Intestinal Disease-Related Stress Responses. Cells. 2016 Sep 10;5(3). pii: E35. doi: 10.3390/cells5030035
https://www.ncbi.nlm.nih.gov/pubmed/27626448

Misiorek JO, Lähdeniemi IA, Nyström JH, Paramonov VM, Gullmets JA, Saarento H, Rivero-Müller A, Husøy T, Taimen P, Toivola DM. Keratin 8-deletion induced colitis predisposes to murine colorectal cancer enforced by the inflammasome and IL-22 pathway. Carcinogenesis. 2016 May 27. pii: bgw063. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/27234655

Desai D, Prabhakar N, Mamaeva V, Karaman DS, Lähdeniemi IAK, Sahlgren C, Rosenholm J, Toivola DM. Targeted Modulation of Cell Differentiation in Distinct Regions of the Gastrointestinal Tract via Oral Administration of Differently PEI-PEG Functionalized Mesoporous Silica Nanoparticles. Int. J. Nanomedicine, 11:299-313, 2016
http://www.ncbi.nlm.nih.gov/pubmed/26855569

Asghar MN, Silvander JS, Helenius TO, Lähdeniemi IA, Alam C, Fortelius LE, Holmsten RO, Toivola DM. The amount of keratin matters in stress protection of the colonic epithelium. PLoS One 10(5):e0127436, 2015
http://www.ncbi.nlm.nih.gov/pubmed/26000979

Helenius TO, Misiorek JO, Nyström JH, Fortelius LE, Habtezion A, Liao J, Asghar MN, Zhang H, Azhar S, Omary MB, Toivola DM. Keratin 8 absence downregulates colonocyte HMGCS2 and modulates colonic ketogenesis and energy metabolism. Mol Biol Cell, 26:2298-2310, 2015
http://www.ncbi.nlm.nih.gov/pubmed/25904331