Nuutinen S, Ailanen L, Savontaus E, Rinne P. Melanocortin overexpression limits diet-induced inflammation and atherosclerosis in LDLR-/- mice. J Endocrinol. 2018 Mar;236(3):111-123. doi: 10.1530/JOE-17-0636. Epub 2018 Jan 9.
Rinne P, Kadiri JJ, Velasco-Delgado M, Nuutinen S, Viitala M, Hollmén M, Rami M, Savontaus E, Steffens S. Melanocortin 1 Receptor Deficiency Promotes Atherosclerosis in Apolipoprotein E-/- Mice. Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):313-323. doi: 10.1161/ATVBAHA.117.310418. Epub 2017 Dec 28.
Rinne P, Rami M, Nuutinen S, Santovito D, van der Vorst EPC, Guillamat-Prats R, Lyytikäinen LP, Raitoharju E, Oksala N, Ring L, Cai M, Hruby VJ, Lehtimäki T, Weber C, Steffens S. Melanocortin 1 Receptor Signaling Regulates Cholesterol Transport in Macrophages. Circulation. 2017 Jul 4;136(1):83-97. doi: 10.1161/CIRCULATIONAHA.116.025889. Epub 2017 Apr 27.
Rinne P, Ahola-Olli A, Nuutinen S, Koskinen E, Eerola K, Juonala M, Kähönen M, Lehtimäki T, Raitakari OT, Savontaus E. Deficiency in Melanocortin 1 Receptor Signaling Predisposes to Vascular Endothelial Dysfunction and Increased Arterial Stiffness in Mice and Humans. Arterioscler Thromb Vasc Biol 2015 Apr 30. pii: ATVBAHA.114.305064
http://www.ncbi.nlm.nih.gov/pubmed/25931512
Rinne PP, Ståhle M, Hellberg S, Silvola J, Salomäki H, Koskinen E, Nuutinen S, Saraste A, Roivainen A, Savontaus E. Pharmacological Activation of the Melanocortin System Limits Plaque Inflammation and Ameliorates Vascular Dysfunction in Atherosclerotic Mice. Arterioscler Thromb Vasc Biol. Jul;34(7):1346-54, 2014
http://www.ncbi.nlm.nih.gov/pubmed/24790139
Rinne P, Nordlund W, Heinonen I, Penttinen AM, Saraste A, Ruohonen ST, Mäkelä S, Vähätalo L, Kaipio K, Cai M, Hruby VJ, Ruohonen S, Savontaus E. α-Melanocyte-stimulating hormone regulates vascular NO availability and protects against endothelial dysfunction. Cardiovasc Res. 97:360-368, 2013
http://www.ncbi.nlm.nih.gov/pubmed/23131503
Rinne P, Penttinen AM, Nordlund W, Ahotupa M, Savontaus E. α-MSH Analogue Attenuates Blood Pressure Elevation in DOCA-Salt Hypertensive Mice. PLoS One 8(8):e72857, 2013
http://www.ncbi.nlm.nih.gov/pubmed/23977363
