TCDM offers multidisciplinary know-how and research services related to studying established mouse models of principal human intestinal disorders including colitis (colonic inflammation, inflammatory bowel diseases) and colon cancer. The unit offers design of experiments including know-how on intestine-related analysis methodology as well as isolation techniques of intestinal epithelial cells.
The intestinal disease models of colitis and colon cancer can be applied e.g. to study:
- Susceptibility of transgenic mice to disease basally or by inducible models
- Susceptibility of wild type mice to disease
- Recovery after disease, eg inflammation
- Effects of therapies